Isaac married Johanna Koehler on 16 Oct 1852 in Monroe County, Ohio, USA. Johanna (daughter of Joseph Koehler and Lydia Schell) was born in 1834 in Monroe County, Ohio, USA. [Group Sheet] [Family Chart]

1. Mathilda Jane Brown was born on 15 Jan 1860 in Ohio, USA; died on 14 Dec 1945 in Lewisville, Monroe County, Ohio, USA; was buried in Buchanan Cemetery, Summit Township, Monroe County, Ohio, USA.