William married Rebecca Cecelia Growden on 5 Jan 1858. Rebecca (daughter of Matthew Growden and Elizabeth Fyock) was born on 18 Aug 1839 in Cumberland Valley, Bedford County, Pennsylvania, USA; died on 17 Apr 1922 in Bedford, Bedford County, Pennsylvania, USA. [Group Sheet] [Family Chart]

1. Matthew Hosea McGuin was born on 19 May 1859 in Bedford County, Pennsylvania, USA; died on 28 Jan 1883 in Pennsylvania, USA.
2. Agnes Melissa McGuin was born on 26 Jan 1861 in Bedford County, Pennsylvania, USA; died on 24 Dec 1949 in Pennsylvania, USA.
3. Clarissa McGuin was born on 30 Mar 1863 in Bedford County, Pennsylvania, USA; died on 27 Aug 1945 in Bedford, Bedford County, Pennsylvania, USA; was buried in Saint Thomas the Apostle Cemetery, Bedford Township, Bedford County, Pennsylvania, USA.
4. William Francis McGuin was born on 5 Mar 1865 in Bedford County, Pennsylvania, USA; died on 19 Feb 1946 in Pennsylvania, USA.
5. Shannon McGuin was born in 1867 in Bedford County, Pennsylvania, USA; died on 14 Jan 1938 in Colorado, USA.
6. James Henry McGuin was born on 31 May 1868 in Bedford County, Pennsylvania, USA; died on 14 Jan 1938 in Lamar, Prowers County, Colorado, USA.
7. Francis John McGuin was born on 8 Jun 1870 in Bedford County, Pennsylvania, USA; died on 16 Jan 1946 in Pennsylvania, USA.
8. Jeremiah Alphonsus McGuin was born on 7 Nov 1872 in Bedford County, Pennsylvania, USA; died on 2 Feb 1932.
9. Mary Josephine McGuin was born on 4 Feb 1876 in Bedford County, Pennsylvania, USA; died on 14 Aug 1943.
10. Teresa Beatrice McGuin was born on 9 Oct 1880 in Bedford County, Pennsylvania, USA; died on 22 Dec 1967 in Bedford County, Pennsylvania, USA; was buried in Saint Thomas the Apostle Cemetery, Bedford Township, Bedford County, Pennsylvania, USA.