Karl married Margaretha Wüst on 23 Feb 1882 in Odessa, Ukrayina. Margaretha (daughter of Heinrich Wüst Wiest and Johanna Hoffmann) was born on 18 Jun 1860 in Rohrbach, Odessa, Ukrayina; died on 1 Sep 1895 in Venturia, McIntosh County, North Dakota, USA. [Group Sheet] [Family Chart]

1. Louisa Gessele was born on 15 Jul 1883 in Odessa, Ukrayina; died on 22 Sep 1969 in McLean County, North Dakota, USA; was buried in Zion Lutheran Cemetery, Mercer, McLean County, North Dakota, USA.
2. Johanna Gessele
3. Edward John Gessele was born on 4 Feb 1887 in Venturia, McIntosh County, North Dakota, USA; died on 7 Feb 1979 in North Dakota, USA; was buried in Mercer Hillside Cemetery, Mercer, McLean County, North Dakota, USA.
4. Karl Gessele
5. Henry Gessele was born on 25 Apr 1890 in Venturia, McIntosh County, North Dakota, USA; died on 27 Feb 1969 in Bismarck, Burleigh County, North Dakota, USA.
6. Rosina Gessele
7. Amelia Gessele

Karl married Christina Bender on 27 Jun 1896 in Ashley, McIntosh County, North Dakota, USA. Christina (daughter of Johannes Bender and Katharina Reuther) was born on 7 Jun 1853 in Kassel, Odessa, Ukrayina; died on 1 Dec 1938 in McLean County, North Dakota, USA; was buried in Bethel United Methodist Cemetery, Mercer, McLean County, North Dakota, USA. [Group Sheet] [Family Chart]